Lactoferrin Chaw tsim tshuaj paus

• Taw qhia Lactoferrin

Lactoferrin, muaj ntau yam hlau-binding glycoprotein feem ntau pom muaj nyob rau hauv cov mis nyuj thiab ntau yam dej hauv lub cev, tau txais txiaj ntsig zoo hauv kev tshawb fawb txog kev tshawb fawb vim nws muaj ntau yam kev ua ub no thiab muaj peev xwm siv tau. Lactoferrin muaj siab nyob rau hauv colostrum thiab mis nyuj, uas tau pom nyob rau hauv cov kua mis los ntawm cov kws tshawb fawb MONTREUIJ thiab JOHANSONB nyob rau hauv 1960. Cov kev tshawb fawb tsis ntev los no tau tso lub teeb rau nws cov txheej txheem ntawm kev ua, nthuav tawm nws txoj kev koom tes hauv kev hloov kho lub cev tiv thaiv kab mob thiab ua rau cov tshuaj tiv thaiv kab mob. Lactoferrin plays lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob hauv lub cev los ntawm sequestering hlau, uas yog qhov tseem ceeb rau kev loj hlob ntawm cov kab mob, yog li txwv tsis pub microbial proliferation.

Lactoferrin Tsim los ntawm Yangge Biotech pab tswj kom cov hlau nqus tau zoo li cas rau hauv lub cev los ntawm txoj hnyuv. Nws kuj zoo li tiv thaiv kev kis kab mob los ntawm cov kab mob, cov kab mob, thiab cov pwm. Cov lactoferrin hauv cov mis niam xav tias yuav pab tiv thaiv cov menyuam mos uas pub niam mis tiv thaiv kev kis kab mob. Tsis tas li ntawd, kev tshawb fawb tau qhia tias lactoferrin muaj cov haujlwm ntawm kev tiv thaiv kab mob dav dav, tiv thaiv kev kis kab mob thiab kev txhim kho kev tiv thaiv kab mob.

• Tus Qauv Zoo ntawm Lactoferrin

Raws li GB1903.17-2016

• zog

Lactoferrin yog ib qho hlau khi glycoprotein nyob rau hauv transferrin, uas yog concentrated nyob rau hauv tib neeg thiab mammalian mis nyuj thiab ntau yam secretory kua. Txawm li cas los xij, cov ntsiab lus hauv colostrum yog qhov siab tshaj plaws. Ib qho me me ntawm lactoferrin kuj muaj nyob rau hauv mammalian mucosal nto, kua muag, qaub ncaug, leukocyte hais, kua txiv pancreatic, kua tsib thiab hnyuv. Nws muaj ntau yam haujlwm, suav nrog kev ua kom tsis muaj menyuam, bacteriostasis, tshuaj tiv thaiv kab mob, tiv thaiv kab mob, txhawb kev nqus hlau thiab lwm yam haujlwm tshwj xeeb ntawm lub cev.

1. Tshuaj tua kab mob

Nws tau raug txiav txim siab tias lactoferrin yog ib tug broad-spectrum bacteriostatic tus neeg sawv cev, uas yuav inhibit Gram-negative kab mob uas yuav tsum tau hlau, xws li coliform, Salmonella, thiab lwm yam; Nws tseem tuaj yeem tiv thaiv kab mob Gram-zoo. Txawm li cas los xij, nws yeej tsis cuam tshuam cov kab mob uas tsis tshua muaj hlau xav tau, xws li cov kab mob lactic acid.

2. Tshuaj tua kab mob

Pioneer Biotech yog Lactoferrin Chaw tsim tshuaj paus. Nws ua lub luag haujlwm tseem ceeb hauv kev tawm tsam cov kab mob hauv tus tswv tsev, thiab tuaj yeem tiv thaiv tib neeg kev tiv thaiv kab mob (HIV), cytomegalovirus, herpesvirus hom 1 thiab 2, kab mob siab C (HCV), kab mob khaub thuas thiab lwm yam. ntawm lactoferrin yog tias lactoferrin tuaj yeem ua ke nrog cov kab mob thiab cov tswv tsev, txhawm rau thaiv kev sib xyaw ntawm cov kab mob thiab cov tswv tsev thiab tiv thaiv tom kawg los ntawm kev puas tsuaj ntawm tus kab mob.

3. Tshuaj tua kab mob

Tshaj oxygen dawb radicals hauv lub cev tsim lipid peroxide, uas tuaj yeem ua rau cov hlwb thiab cov ntaub so ntswg puas. Nws yog ib qho cim ntawm kev laus thiab kab mob. Lactoferrin tuaj yeem khi hlau ions thiab thaiv cov lipid oxidation thiab ciaj sia hloov pauv ntawm cov pa dawb radicals los ntawm cov hlau ions. Tag nrho cov no tuaj yeem txo qhov kev puas tsuaj ntawm cov dawb radicals rau elastin hauv cov phab ntsa ntawm cov hlab ntsha, txhawm rau tiv thaiv thiab kho atherosclerosis thiab kab mob plawv.

4. Tswj kev tiv thaiv kab mob

Lactoferrin tuaj yeem ua ke nrog cov lymphocytes, monocytes, macrophages thiab lwm cov hlwb los ua ntau yam haujlwm. Lactoferrin tuaj yeem ua rau lub cev tsis muaj zog, txhawb cov lymphocyte proliferation, tswj cov pob txha pob txha ntawm tes thiab txo qhov mob. Nyob rau tib lub sijhawm, lactoferrin tuaj yeem tua cov kab mob los ntawm kev txhawb nqa neutrophils los tsim peroxides. Lactoferrin tuaj yeem ua rau muaj kev loj hlob ntawm cov hnyuv mucosal thiab cov hlwb spleen thiab txhawb kev loj hlob ntawm cov kab mob hauv plab hnyuv.

5. Tiv thaiv kev loj hlob ntawm mob qog noj ntshav.

Lactoferrin yog ib qho hauv vitro broad-spectrum tshuaj tua kab mob ntawm tib neeg thiab tsiaj cov kab mob raws li DNA / RNA. Tiv thaiv: herpes simplex virus type I thiab II, cytomegalovirus, human immune deficiency virus, hepatitis C virus, hantavirus, rotavirus, poliovirus type I, human respiratory syncytial virus and murine leukemia virus.

Tau qhov twg los: https://www.spandidos-publications.com/10.3892/ijo.2021.5265

6. Tswj kev nqus hlau

Raws li cov hlau fortifier, cov nyhuv nqus ntawm lactoferrin zoo dua li ntawm ferric sulfate. Lactoferrin muaj peev xwm khi thiab thauj hlau. Nws tuaj yeem tso tawm cov hlau tom qab ncav cuag tib neeg txoj hnyuv, uas tuaj yeem txhim kho qhov nqus thiab bioavailability ntawm hlau.

7. Lactoferrin rau kev kho mob COVID-19

Tsis ntev los no, cov kws tshawb fawb Asmeskas tau siv thev naus laus zis thev naus laus zis los tshuaj xyuas ntau yam tshuaj uas tuaj yeem cuam tshuam nrog COVID-19, suav nrog lactoferrin.

Tau qhov twg los: https://www.spandidos-publications.com/10.3892/etm.2020.9402

• Siv rau lactoferrin

1. Kev noj haus rau menyuam yaus

yog lub khw tseem ceeb rau kev siv lactoferrin. Txawm li cas los xij, lwm cov sectors siv cov khoom noj khoom haus thiab kev ua haujlwm ntawm cov protein no.

2. Lactoferrin yog siv dav ua khoom noj khoom haus ntxiv.

Tshwj xeeb yog ib qho immunomodulator. Txawm hais tias nws cov yeeb yam tseem tsis tau to taub meej, peb paub tias nws txhawb kev tiv thaiv kab mob. Ob txoj kev tshawb fawb tau ua rau cov neeg ua haujlwm noj qab haus huv tau pom tias kev noj nyuj cov mis nyuj lactoferrin muaj cov tshuaj tiv thaiv kab mob zoo (nyob ntawm qhov pib ntawm tus neeg ua haujlwm pab dawb lub cev tiv thaiv kab mob). Cov txiaj ntsig tau qhia tias nyuj cov mis nyuj lactoferrin tuaj yeem siv rau hauv kev kho mob los txhim kho kev tiv thaiv kab mob ntawm cov neeg mob thiab tseem tuaj yeem ua lub luag haujlwm hauv kev ua kom lawv lub cev tiv thaiv kab mob. Cov tshuaj Lactoferrin tam sim no raug muag twb muaj ib theem ntawm purity mus txog 96%.

3. Lactoferrin kuj tseem siv rau hauv kev lag luam tshuaj pleev ib ce

Nws tuaj yeem pom muaj nyob rau hauv ntau yam khoom siv zoo nkauj xws li pleev thiab plaub hau, lub ntsej muag thiab lub cev saib xyuas. Piv txwv li, nws cov khoom tua kab mob txhais tau tias nws yog ib qho khoom xyaw nrhiav tom qab hauv cov tshuaj ntxuav. Nws kuj tseem siv rau hauv cov mis tshuaj tsuag plaub hau rau kev ua kom cov plaub hau noo thiab du. Lactoferrin kuj tseem ua rau cov tawv nqaij metabolism thiab muaj cov nyhuv tiv thaiv kev laus vim nws cov khoom antioxidant uas ntes cov free radicals.

4. Cov chaw tu cev qhov ncauj kuj siv cov lactoferrin

Lactoferrin muaj kev sib raug zoo rau hlau, pab nws ua tus neeg sawv cev bacteriostatic. Nws ua tau txo qhov ntau ntawm cov dawb ferric ions, inhibiting kev loj hlob ntawm cov kab mob thiab lwm yam teeb meem xws li ua tsis taus pa, hniav caries thiab tartar.

Txaus Daim Ntawv

Txoj kev tsom xam ntawm Lactoferrin

1. Txoj kev

Siv HPLC ntsuas, kuaj cov lactoferrin ntawm 280nm nrog thaj tsam normalization txoj kev.

2. Npaj cov khoom

2.1 Qib 1 dej.

2.2 HPLC Acetonitrile XNUMX.

2.3 0.9% NaCl tov

2.4 1% trifluoroacetic acid tov: noj 1ml trifluoroacetic acid tov, dilute nrog qib 1 dej mus rau 100ml, mus nrog 0.45μm lim membrane.

2.5 HPLC ntsuas nrog UV ntes.

3. Chromatographic mob

3.1 Chromatographic kab:

Alltech prosphere C4 300A (150mmx4.6mm),

Alltech All-guardTM Guard (7.5mm x4.6mm), los yog tib lub luag haujlwm kem.

3.2 Ntes wavelength: 280nm.

3.3 Flow tus nqi: 1.0ml / min.

3.4 Kem Kub: 35 ° C.

3.5 Txhaj Volume: 50μl.

3.6 Gradient elution tsis.

4. Cov kauj ruam xeem

Siv cov qauv thiab lactoferrin tus qauv siv 0.1g txhua, ob qho tib si ntxiv 10ml qib 1 dej (lossis NaCl tov), ​​thiab mus txog 0.45μm lim membrane, tom qab ntawd peb tau txais cov qauv kev daws teeb meem thiab kev siv tshuaj. Siv 50μl txhua los ntsuas ntawm 280nm, thiab ua tib lub sijhawm ntxiv (kwv yees 10min). Lub ncov tseem ceeb yog lub ncov ntawm Lactoferrin. Xam tag nrho cov cheeb tsam ncov ntawm ob zaug ntxiv. Qhov piv ntawm lub ntsiab ncov cheeb tsam thiab tag nrho cheeb tsam ncov yog qhov kev ntsuam xyuas lactoferrin tawm ntawm tag nrho cov protein.

• Reference Chromatogram ntawm Lactoferrin Reference Khoom

Kev ruaj ntseg thiab kev nyab xeeb

1. Stability: Nyob ruaj khov nyob rau hauv cov xwm txheej zoo (chav kub). Cov Ntaub Ntawv Kev ruaj ntseg muaj nyob rau ntawm koj qhov kev thov.
2. Kev Nyab Xeeb: Raws li GARS (Feem ntau pom tau tias muaj kev nyab xeeb) Daim Ntawv Ceeb Toom ntawm Teb Chaws Asmeskas, nws muaj kev nyab xeeb rau tib neeg noj.

Pob Lactoferrin

Lactoferrin ntim ua lub luag haujlwm tseem ceeb hauv kev khaws cov khoom tshiab, zoo, thiab lub neej txee. Xav txog cov khoom ntim hauv qab no:

Ntim rau hauv ntau txheej kraft ntawv hnab nrog zaub mov qib PE puab lub hnab, nqa 25kg / hnab. (Lwm hom ntim khoom muaj nyob ntawm kev thov)

Yuav Lactoferrin qhov twg?

Koj tuaj yeem yuav Lactoferrin ntawm yog yanggebiotech.com Lub tuam txhab yog cov chaw tsim khoom lag luam ua lag luam thiab xa tawm rau cov tshuaj ntxiv. yog yanggebiotech.com tsis yog ib hom neeg siv khoom xwb. yog tshwj xeeb rau kev muab ntau tshaj 300 cov khoom xyaw ntuj. Nws kuj tseem muab cov khoom xyaw ntshiab rau lwm lub npe uas faib khoom noj thiab lwm yam khoom ntxiv.

Hu rau yanggebiotech.com kom tso ib qho kev txiav txim hnub no.